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StuthiIyer,MPH1; Jason N.Kennedy,MS1; Jacob C.Jentzer,MD2; et al Mourad H.Senussi,MD, MS3; Christopher W.Seymour,MD, MSc1
Author Affiliations Article Information
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1Department of Critical Care Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania
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2Department of Cardiovascular Medicine, Mayo Clinic College of Medicine and Science, Rochester, Minnesota
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3Department of Medicine, Baylor College of Medicine, Houston, Texas
JAMA. Published online April 8, 2024. doi:10.1001/jama.2024.3917
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Between 2009 and 2014, 21% of US adults with sepsis did not survive.1 Guidelines recommend urgent resuscitation of patients with sepsis, although the ideal treatment regimen is not clear2 and challenges to resuscitation, including the management of sepsis-related cardiac dysfunction, remain.3 How preexisting cardiac disease is associated with outcomes is poorly understood. This study characterizes heterogeneity in cardiac function prior to sepsis and describes associations with hospitalization outcomes and mortality.
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Resuscitation Critical Care Medicine Infectious Diseases Sepsis Cardiology
Citation
Iyer S, Kennedy JN, Jentzer JC, Senussi MH, Seymour CW. Cardiac Function Before Sepsis and Clinical Outcomes. JAMA. Published online April 08, 2024. doi:10.1001/jama.2024.3917
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